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Our Lady of Guadalupe appeared to Juan Diego on Mount Tepeyac in Mexico. 
When Juan Diego was concerned by the illness of his uncle she told him: 
"Hear me and understand well, my son, that nothing should frighten or grieve you. Let not your heart be disturbed. 
Do not fear sickness, nor any other anguish. 
Am I not here, who is your Mother? 
Are you not under my protection? 
Am I not your health? 
Are you not happily in my fold, here in the crossing of my arms? 
What else do you wish?
Amen